‘cancer treatment’

Clinical Trials

Wednesday, June 16th, 2010

Clinical TrialsClinical Trials

Anal cancer stage I was formerly treated with abdominoperineal resection. Current therapies in preserving the sphincter include wide local excision of the perianal skin or anal margin for small tumors, or definitive chemoradiation (fluorouracil, and mitomycin) for cancers of the anal canal. Salvage chemoradiation therapy (fluorouracil and cisplatin plus a radiation boost) may avoid permanent colostomy in patients with residual tumor after undergoing initial nonoperative therapy. Radical resection is reserved for patients with incomplete responses or recurrent disease. It is therefore important continuous surveillance with rectal examination every three months during the first two years and endoscopy / biopsy when indicated after completion of sphincter-preserving therapy.

Standard treatment options:

1. Small tumors of the perianal skin or anal margin not involving the anal sphincter may be adequately treated with local resection. (more…)

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Anal Cancer Details

Sunday, June 13th, 2010

Anal Cancer DetailsAnal cancer is a disease in which malignant cells form (cancer) in the tissues of the anus.
The anus is the end point of the large intestine, below the rectum, through which the body dismissed the stool (solid waste). The anus is formed partly by the outer layers of skin on the body and partly from the intestine. Two ring-shaped muscles, called sphincter muscles, open and close the anal opening to allow stool to be evacuated from the body. The anal canal, the part of the year that lies between the rectum and the anal opening, is about 1 ½ inches long.
Anatomy of the lower digestive system, showing the colon and other organs.

The skin around the outside of the anus is called the perianal area. Tumors in this area are skin tumors, not anal cancer.

Being infected with the human papillomavirus (HPV, for its acronym in English) may influence the risk of anal cancer.

Among the risk factors include: (more…)

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Standard Treatment

Thursday, June 10th, 2010

PHASE II-Standard TreatmentCANCER OF THE YEAR – PHASE II
Anal cancer stage II were formerly treated with abdominoperineal resection. Current therapies in preserving the sphincter include wide local excision of the perianal skin or anal margin for small tumors, or definitive chemoradiation (fluorouracil, and mitomycin) for cancers of the anal canal. Salvage chemoradiation therapy (fluorouracil and cisplatin plus a radiation boost) may avoid permanent colostomy in patients with residual tumor after undergoing initial nonoperative therapy. Radical resection is reserved for patients with incomplete responses or recurrent disease. It is therefore important for continued vigilance with rectal examination every 3 months during the first 2 years and endoscopy / biopsy when indicated after completion of therapy for sphincter preservation.

Standard treatment options:

1. Small tumors of the perianal skin or anal margin not
involving the anal sphincter may be adequately treated with local resection. (more…)

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Overview of Treatment Options

Monday, June 7th, 2010

Overview of Treatment Options Previously it was thought that abdominoperineal resection leading to permanent colostomy was required for all except small anal tumors located below the dentate line, treatment with which about 70% of patients survived five years or more in institutions, but such surgery is no longer the preferred treatment. Radiation therapy alone may lead to a survival rate five years in more than 70%, although high doses (6,000 cGy or more) may cause necrosis or fibrosis. Chemotherapy concurrent with low-dose radiation therapy have led to a survival rate five years more than 70% with low level of acute and chronic morbidity, and few patients require surgery due to the toxic effects dermal or sphincter. Still being evaluated the optimal dose of radiation concurrent with chemotherapy to optimize local control and minimize sphincter toxic effects, but appears to be between 45 and 60 Gy. The analysis of a test between groups that compared radiation therapy plus fluorouracil / mitomycin with radiation therapy plus fluorouracil alone in patients with anal cancer has shown better results by adding mitomycin (lower colostomy rates and longer survival and disease-free colostomy). Radiation with continuous infusion of fluorouracil plus cisplatin is also under evaluation. The standard salvage therapy for patients with residual disease, either gross or microscopic chemoradiotherapy was followed by (more…)

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STAGE INFORMATION

Friday, June 4th, 2010

STAGE INFORMATION The anal canal extends from the rectum to the perianal skin, and is lined by a mucous membrane that covers the internal sphincter. Below is a classification system for anal canal cancer has been described by the American Joint Committee on Cancer (AJCC by its acronym in English) and the International Union Against Cancer. Margin tumors anal (located below the anal verge and involving the perianal skin with hair) are classified with skin tumors.

TNM Definitions
Primary tumor (T)

TX: Can not evaluate the primary tumor
T0: No evidence of primary tumor
Tis: Carcinoma in situ
T1: Tumor 2 cm or less in greatest dimension (more…)

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Broccoli Helps Fight Cancer

Thursday, May 6th, 2010

Broccoli Helps Fight Cancer

Broccoli contains a substance that can fight cancer and prevent experts say at least.

And laboratory mice
Scientists tested the effects of sulforaphane, a compound in broccoli, in experiments with mice and cell cultures. They injected various concentrations of the component from broccoli in mice with breast cancer. This shows that the stem cells of cancer decreased after treatment with this substance, this had little effect on normal cells. Unlike chemotherapy, which causes the patient after treatment often feel ill. (more…)

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The Role of Exercise During Cancer Treatment

Monday, May 3rd, 2010

The Role of Exercise During Cancer Treatment

Vigor Orbis, Orbis and Orbis Sports Medical Center will participate in research on effects of physical training during treatment cancer.

The Role of Exercise During Cancer TreatmentAlthough such research non-core part, we are pleased to deliver a contribution. This consists of project management at the research site Orbis Medical Center and conducting intakes, times of measurement and evaluation with the participants. We will keep you informed of the results. The study called PACT (Physical Activity consistently Cancer Treatment) is an initiative of the Comprehensive Cancer Centre Middle Netherlands and Limburg in collaboration with the University Medical Centre Utrecht and Maastricht. (more…)

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Head and Neck Cancer

Wednesday, April 21st, 2010

Cancer in the head and neck cancer includes cancer of the mouth, nose, sinuses, salivary glands, throat and lymph nodes in the neck. Most begin in the moist tissues around the mouth, nose and throat. Symptoms include:

* A lump or sore that will not heal
* Sore throat that does not go away
* Difficulty swallowing
* Voice changes or hoarseness (more…)

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A vaccine will cure skin cancer

Thursday, April 15th, 2010

A new vaccine being tested gives new hope for treatment of skin cancer. The drug, called “OncoVEX” attacks cancer cells, leaving healthy cells intact, and stimulates the body’s response to melanoma, so patients can fully recover, even those with the disease, advanced.

Dr. Howard Kaufman of the Rush University Medical Center in Chicago said that the vaccine will bring relief to thousands of people with skin cancer every year. The drug not only affects cells that are injected, but also in other parts of the body can not be reached, inducing an immune response by the flow of blood.

The BioVex, manufacturer is currently recruiting more than 400 patients for the final stages of testing, which will be made in the USA and the UK. (more…)

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Found a cure for skin cancer

Monday, April 12th, 2010

A test vaccine in infancy in England shows its effect has some complete cures melanoma, even at an advanced stage: attack cancer cells while leaving healthy cells intact and significantly increases the immune response to skin cancer.

Dr. Howard Kaufman of Chicago’s Rush University Medical Center, says: “Our studies show clearly that we are: we have a cure for melanoma and develop drugs that could save thousands of lives every year.”

The figures are dramatic: in the last 25 years the rate of melanoma in the UK alone has increased dramatically compared to other types of cancer, and kills more than 2,000 victims a year. (more…)

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