Posts Tagged ‘Breast Cancer’
Soy to prevent breast cancer
The benefits of soy in relation to cancer and are known to science for some time, and recently made an investigation highlighted its importance in preventing colon cancer . In this case, follow the same line in cancer prevention, but this time in relation to breast cancer.
Breast cancer, one of the most common among women and one that takes more victims per year can be prevented to some degree with proper nutrition and a healthy lifestyle. Among the foods to prevent breast cancer are soybeans, which once again demonstrates its utility for health.
In research conducted by Chinese researchers who published their study in JAMA , was conducted to test women with breast cancer who were offered soy to feed, and then measured the rate of mortality and aggravation of the disease.
It was found that women who were fed soy had a 29% lower risk of mortality during the study period, plus 32% fewer cases of re-emergence of the disease.
The results are clear, and once again stop the soy goes well. Are soy isoflavones the food that make it as healthy and preventing associated with many diseases.
Breast cancer mortality reduction
The mortality rate in cancer dropped 7% during 2002-2006, from 17.9 deaths to 16.7 deaths per 100,000 persons. These data come from a study that was conducted by the Institute of Social and Preventive Medicine of the University Teaching Hospital Vaudois, in Lausanne, in collaboration with researchers from Italy.
Observation
A decrease in the number of deaths was higher among young women aged 20 to 49 years (from the European Union) or because of -11.6%. With regard to women 50 to 69 years, the reduction was more restricted to the tune of -6.6%.
Although the reduction in deaths is positive, it is important to note that breast cancer remains the main cause of deaths among women in Europe.
This decrease continued throughout the past decades is due to the advancement of therapeutic approaches available. This trend is sign of hope, because the European Union called for a reduction of 9% between 2006 and 2012. If this rate continues to drop, it is planned for late 2012, that 25 000 deaths are prevented annually.
Improved treatment of childhood cancer through research
The Association of Children and Health organized a national conference on cancer and leukemia in children. Participants emphasized the importance of research in the field of cancer, which has reduced the mortality rate associated with this type of pathology.
Research conducted for several years have improved the management of childhood cancers and to develop specialized medical institutions
More accurate analysis
The advance in the field of childhood cancers allow researchers to conduct toxicology tests more accurate. The results of these analyzes facilitate the management of the disease . They also help reduce the severity of complications. Moreover, with concise information, it is possible to choose a suitable therapy.
Treatment of Burkitt’s lymphoma
Methods of treatment of Burkitt’s lymphoma are now less dangerous compared to those used in the 70s. Prolonged chemotherapy used in the past involved risks particularly at heart. The mortality rate was very high. Used in recent years new methods of safer and more effective. These methods combine the use of drugs such as methotrexate, used with high-dose chemotherapy. They increased the cure rate to over 75%.
New genetic clues are detected on breast cancer
Breast cancer is the cancer most often affects women (in fact, one in eight women in the world), and is the second leading cause of death among women worldwide. The risk of contracting it increases with age and is 2 to 4 times higher in women with a family history. The study of genetic predisposition is critical to identify gene mutations that increase the risk, either to take the necessary preventive measures, or adopt a more aggressive treatment for newly diagnosed cancer. To those already identified by scientists, just join three other genomic regions associated with breast cancer. Find it here. Saved at the core of each of our cells is the code that identifies us as a species and as individuals. Are our genes, inherited from our ancestors. We owe them our features, from height and eye color and skin to hair texture. They also owe susceptibility to certain diseases, including cancer. Thus, the study of our genetic map is a useful tool in the medical field, especially in the area of prevention. As scientists gain more information about our genes, the more effective the treatments to prevent and combat diseases that claim many lives as breast cancer, as we said, is the most common among women and reported that around 1 million new cases per year and causes about 400 000 deaths worldwide.
Although most breast cancers are of a sporadic (not related to inheritance), about 10% of cases, especially in women under 40 years, yes there is a genetic or hereditary predisposition (in these cases, the mother, daughter or sister of the patient has had breast cancer). Two thirds of these cancers are due to inherited mutations (or changes) of two specific genes called BRCA1 and BRCA2.
Fortunately, the genetic map is still revealing its secrets. Research conducted at the University of Cambridge, England recently discovered three new areas in the genome (ie, in our DNA sequence accumulated on chromosomes where genes are concentrated) that may increase the risk of developing cancer breast. Had previously identified 22 loci of susceptibility to breast cancer. A locus (means place or location, in Latin and its plural is loci). With the discovery of three new loci that number rises to 25 points of susceptibility that could explain about 9% of familial risk of breast cancer. Although the researchers admit that the impact on number of cases is relatively low, the contribution remains important in understanding the complex mechanism behind cancer and improve treatment and patient care.
For example, an area or locus has been identified is related to breast cancer estrogen receptor positive (estrogen needed for growth) and also in estrogen receptor negative. Another variant was found in a gene which plays a role in the development of mammary glands and bone. The study authors point out that it was known that the development of the mammary gland at puberty is an important step in determining the subsequent risk of cancer, but the first time it is shown that these specific genes are related to the process. These and many more details about the research are published in the January issue of the journal Nature Genetics.
The complicated and fascinating story of the genome is opening up its doors, offering new options for testing and therapy and new drugs to attack cancer more effectively.
The goal, of course, remains disposal. But until that day comes, learn and take care. Learn how to perform breast self-exams, get mammograms recommended for your age, know your risk factors and takes an active and healthy.
Let’s Talk About Cancer
Cancer now dominates our community, cases are displayed in abundance in all parts of the world. Most individuals affected with this disease live with it without knowing it. For now, cancer has been considered a disease death in the world with their performance. This gradually suppress the immune system.
Research shows that cancer is “an abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize.” And we know that cancer is not just a disease actually a group. This growth was the name of a crab.
Any abnormal growth of tissue was appointed through the organ. For example, when the mother happened to have abnormal growth, then this will be diagnosed as breast cancer, as with the prostate, lung, skin, ovaries and so on.
We refer to a tumor or neoplasm or malignant, which means a disease that can grow and progress continually. Some people have no idea perplexed when it comes to benign tumors. A benign tumor is not as bad as you think, not cancer at all, and certainly the two types are not contagious.
Factors that cause inflammatory breast cancer were identified
Researchers at the University of Medicine in New York in the United States have identified factors that cause the incidence of inflammatory breast cancer, a deadly disease that is the growth of cancerous tissue derived metastases usually very quickly in the body patient .
The study was published in the journal “Nature” data giving information about this type of cancer and their origins .
On the one hand it was found that breast cancer is inflammatory consequence of excess protein identified as eIF4GI. This protein on the one hand help to make cancer cells more adhesive and is rapidly transformed into metastatic tumors.
Worth noting the extremely malignant nature of this type of cancer, at the same time represents between 1 and 2 percent of breast tumors that invade the body affected .
Arimidex in the treatment of breast cancer
As reported in the British Journal of Cancer (BJC), confirming that Arimidex (anastrozole) is an effective treatment for early breast cancer.
Arimidex is evident that offers a cost-effective alternative to tamoxifen in the adjuvant treatment of postmenopausal women with early breast cancer hormone dependent.
Arimidex continues to be the first and only aromatase inhibitor whose efficacy and safety have been extensively tested for over 5 years initial adjuvant therapy in postmenopausal women with breast cancer.
Treatment with this drug should be provided as soon as possible to reduce significantly the risk of breast cancer recurrence, while minimizing the risk of serious adverse effects.
Genes that trigger breast cancer risk
Researchers have studied the interaction of four genes identified as likely to trigger the most common tumor and feared by women, breast cancer.
The four identified genes, called FGFR2, TNRC9, MAP3K1 and LSP1 are related to the organic processes of growth and cell signaling, aspects that had not been deepened too.
The genetic pathway for the repair of DNA damage has been the most studied so far.
The idea is to decipher the genetic profile of susceptibility to breast cancer.
It is estimated that some 200 genes may be susceptibility and combinations of between 6 and 10 of these genes in a person would represent a significant risk of eventually develop a tumor.
Are beginning to identify genes and will soon be able to know what happens when a person is 2, 5 or 10 genes of these característicasta.
In the medium term, perhaps five years, this profile can be well defined and could be ready for implementation in clinical practice to identify high-risk women and early detection of tumor.
Once upon a time in San Antonio
San Antonio is a Texas city with few attractions, apart from the archaeological remains of the battle of the Alamo. However, few are dedicated to breast cancer pilgrimage there almost every year. The reason is the international symposium on breast cancer, the most important of all dedicated to the most common malignant tumor of women, the global meeting of experts where they reveal the results of more substantial research.
On 10 December, Dr. Josep Baselga (Hospital Vall d’Hebron Hospital in Barcelona and Massachusetts in the U.S.) occupied the central lectern ‘of SanAntonio’ to communicate the results of neo-ALTTO trial. This is a coordinated effort of 24 countries in Europe, America and Asia, with a huge turnout of SOLTI, a group of researchers from spain. Read the rest of this entry »
What Is Breast Cancer?
Breast cancer is an abnormal and disordered growth of cells in this tissue.
The breast is composed of a series of mammary glands that produce milk after birth, and which are called lobes and lobules.
The lobes are connected by tubes, ducts, which are those that carry milk to the nipple during lactation, to feed the baby.
The glands and the ducts are embedded in adipose tissue and connective tissue, which, together with the lymphatic tissue, form the breast.
A retaining wall as it acts pectoral muscle which lies between the ribs and breast.
Skin lines and protects the entire breast structure.
The lymphatic system consists of containers and vessels or tubes that contain and carry the lymph, a colorless liquid made up of white blood cells, mostly lymphocytes. These cells recognize any foreign substance to the body and release substances that destroy the offending agent.