Lung cancer may have genetic causes
Smoking is the most frequent cause of lung cancers, but there is a significant number of people developing the disease too, having never smoked. Even if another risk factor for non-smokers is passive smoking, there is another cause that can cause cancer, without there ever having been exposed to tobacco smoke.
A percentage of 30% of patients with lung cancer, it would be for a genetic cause. To find U.S. researchers who have found genetic variations responsible for these cases of lung cancer.
Dr. Ping Yang and colleagues at the Mayo Clinic in Rochester have found that the variations on chromosome 13, alterebbero the GPC5 that, because of its failure would no longer be able to serve as an immunosuppressant cancer, increasing by almost 60 % the risk of developing lung cancer among non-smokers.
The details of this work have been published in the journal Lancet Oncology.
Lung cancer is the second most common type of cancer among men and third among women