Leukemia is a malignant disease, a progressive on the organ – the organ of blood formation marked by the proliferation and development of leukocytes and abnormal predecessor in the blood and spinal cord. Cell proliferation of abnormal leukocytes, malignant, often accompanied by leukocytes that do not form abnormal, excessive amounts, can, causing anemia, thrombocytopenia, and ends with the death (Mansjoer, 1999).
By type, leukemia can be divided into mieloid and lymphoid leukemia. Each is an acute and chronic. In general, the division of leukemia are as follows, namely: Lymphoid leukemia:
Limfoblastik Acute leukemia (LLA)
Cancer is the most frequently attacks children under the age of 15 years, with a peak incidence between the ages of 3 to 4 years.
LLA is a manifestation of the proliferation of abnormal limpoblas sum-sum in the bone and ekstramedular places. Most often occurs in male than female, rare LLA (Smeltzer and Bare, 2001).
The first symptoms usually occur because the bone marrow fails to produce red blood cells in sufficient quantities, namely: weak and shortness of breath, due to anemia (red blood cells are too small) and fever due to infection, decreased white blood cell count of bleeding, because the number of platelet too little.
Clinical manifestations:
Obstructed normal Hematopoesis
Decrease in the number of leukocytes
Decrease in red blood cells
Decreased platelet
Tags: leukemia, Limfoblastik Acute, Limfoblastik Acute leukemia, mieloid and lymphoid leukemia
