Anal Cancer
Oral cavity cancer and smoking
Oral cancer is a destructive disease in the region of the head and neck can infiltrate and invade tissues and spread to other areas via the lymphatic and blood, resulting in distant metastases.
Each puff of smoke fills the mouth before being sucked into the lungs. The largest concentration of toxic substances is evidently in the mouth and attacks the mucous membranes.
Smoking snuff causes oral cavity cancer in men and women. The risk increases when consumed smokeless snuff or smoking and drinking alcohol.
here is a strong relationship between cancer risk and how many cigarettes are smoked and for how long. The risk tends to decrease once you stop smoking.
Most cancers of the buccal cavity birth caught flat cells that line the interior of the mouth.
Mouth cancer is manifested by a tumor can be placed on the lips, tongue, inner walls of the cheeks, gums and palate.
Causes
The main causes of oral cancer include:
- Consumption of snuff (90% of oral cancer due to smoking cigarettes, cigars or pipes, chewing snuff and snuff powder rubbed on the gums).
- The consumption of alcohol.
- Leukoplakia – a condition characterized by a whitish patch that develops inside the mouth or throat.
- Erythroplakia – a condition characterized by red, raised patch that develops inside the mouth.
- Excessive sun exposure as anywhere in the body, can cause lip cancer.
- Red or white patches velvety texture
- Ulcers or sores that fail to heal
- Plate-like sores or warts on the lips
- Persistent sore throat
- Lump on the lip, on the tongue or neck
- Difficulty chewing, swallowing or talking
- Descrecimiento not painful in the lip, forming a dry scab that bleeds when removed
- Pain in the ear or jaw
Clinical Trials
Clinical Trials
Anal cancer stage I was formerly treated with abdominoperineal resection. Current therapies in preserving the sphincter include wide local excision of the perianal skin or anal margin for small tumors, or definitive chemoradiation (fluorouracil, and mitomycin) for cancers of the anal canal. Salvage chemoradiation therapy (fluorouracil and cisplatin plus a radiation boost) may avoid permanent colostomy in patients with residual tumor after undergoing initial nonoperative therapy. Radical resection is reserved for patients with incomplete responses or recurrent disease. It is therefore important continuous surveillance with rectal examination every three months during the first two years and endoscopy / biopsy when indicated after completion of sphincter-preserving therapy.
Standard treatment options:
1. Small tumors of the perianal skin or anal margin not involving the anal sphincter may be adequately treated with local resection. Read the rest of this entry »
Anal Cancer Details
Anal cancer is a disease in which malignant cells form (cancer) in the tissues of the anus.
The anus is the end point of the large intestine, below the rectum, through which the body dismissed the stool (solid waste). The anus is formed partly by the outer layers of skin on the body and partly from the intestine. Two ring-shaped muscles, called sphincter muscles, open and close the anal opening to allow stool to be evacuated from the body. The anal canal, the part of the year that lies between the rectum and the anal opening, is about 1 ½ inches long.
Anatomy of the lower digestive system, showing the colon and other organs.
The skin around the outside of the anus is called the perianal area. Tumors in this area are skin tumors, not anal cancer.
Being infected with the human papillomavirus (HPV, for its acronym in English) may influence the risk of anal cancer.
Among the risk factors include: Read the rest of this entry »
Anal Cancer
GENERAL INFORMATION
Anal cancer is often curable. The three major prognostic factors are site (anal canal versus perianal skin), size (primary tumors less than 2 cm have a better prognosis) and differentiation (well differentiated tumors have a better prognosis than tumors with poor differentiation).
Anal cancer is an uncommon malignancy that represents only a small percentage (4%) of all cancers of the lower digestive tract. Some clinical trials have evaluated the role of chemotherapy, radiotherapy and surgery in the treatment of this disease. If you need information about ongoing clinical trials of the NCI.
In general, the risk of anal cancer is increasing, and there is evidence that individuals with human papillomavirus and gay men in particular are at increased risk of autism.
CELLULAR CLASSIFICATION
Squamous cell carcinomas (epidermoid) constitute the vast majority of all primary cancers of the anus, Read the rest of this entry »
Anal Cancer
Anal cancer is often curable. The three major prognostic factors are site, size and differentiation.
Cancer of the anus is a rare malignancy, representing only a small percentage (4%) of all cancers of the lower digestive tract
In general, the risk of anal cancer is increasing, and there is evidence that individuals with human papillomavirus and gay men in particular are at increased risk of autism. Read the rest of this entry »