Anal Cancer
GENERAL INFORMATION
Anal cancer is often curable. The three major prognostic factors are site (anal canal versus perianal skin), size (primary tumors less than 2 cm have a better prognosis) and differentiation (well differentiated tumors have a better prognosis than tumors with poor differentiation).
Anal cancer is an uncommon malignancy that represents only a small percentage (4%) of all cancers of the lower digestive tract. Some clinical trials have evaluated the role of chemotherapy, radiotherapy and surgery in the treatment of this disease. If you need information about ongoing clinical trials of the NCI.
In general, the risk of anal cancer is increasing, and there is evidence that individuals with human papillomavirus and gay men in particular are at increased risk of autism.
CELLULAR CLASSIFICATION
Squamous cell carcinomas (epidermoid) constitute the vast majority of all primary cancers of the anus, forming the rest are an important subgroup of tumors cloacógenos (basaloid transitional cell). These two histologic variants are associated with human papillomavirus infection. [1] Adenocarcinomas from anal glands or fistulae formation and melanomas are rare. This summary does not include information on the treatment of anal melanoma.